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Useful Information

Dear HBC Protocols, Your sceletium plant was developed to be higher (in Mesembrenol and Mesebrone and lower in Mesbrine) Does Zembrin’s sceletium tortuosum have a more specific name? No, it is the cultivar chosen based on collaboration with the indigenous people of South Africa. What is the alkaloid content of the various actives? Looking at our most recent version of the SIDI for sceletium extraction, here is the content of the 4 major alkaloids : mesembrine, mesembrenone, mesembrenol, mesembranol: Total alkaloids: 0.35-0.45% Mesembrenol + Mesembrenone NLT 60% of total alkaloid Mesembrine NMR 20% of total alkaloid Mesembranol : present It is important to note that sceletium varies significantly in total alkaloid content 0.05 – 2.3% as well as alkaloid composition (eg. mesembrine may be 0-90% of total alkaloids). So, it is significant that the cultivar chosen to be used in Zembrin has a low mesembrine content and that the final

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Helpful Points

Here are some additional points which might be helpful to you: Zembrin is made from a traditionally used plant variety that is not traditionally fermented While fermentation is discussed on internet websites etc, to this day there is no publication yet describing the chemistry of traditionally fermented Sceletium. No one yet knows what the chemistry is meant to be, or what processes are involved, and how to reproduce these on a commercial scale. The Zembrin selection is suitable for once a day dosing. Zembrin to date is the only Sceletium product in the world to have published pharmacology and a published clinical trial, with two pending publications on two additional clinical trials. Barbara Davis, PhD, RD Director, Medical & Scientific Affairs